3DPatch is an application facilitating residue-level information content calculations, homology searches, and 3D structure conservation level-based mark-up for protein sequence or profile hidden Markov model (HMM) queries.

Find out more about 3DPatch in Help or in the 3DPatch Bioinformatics paper.


Start new search

Enter a protein sequence[Help]

Or upload a profile HMM file

Load state

Upload a save point file[Help]

Profile HMM information content profile

Profile HMM structure coverage

Click on a box to view the structure[Help]

Looking for a different structure ? Select it below

See which of these PDB chains have the same sequence here.


Sequence alignment

Select a PDB chain residue to see it highlighted in the viewer[Help]

Structure viewer

Change the information content color scaling method[Help]